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Browsing by Author "Atsma, F."
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Physical exercise prior to hematopoietic stem cell transplantation: A feasibility study. Haren, I.E.P.M. van ; Staal, J.B. ; Potting, C.M. ; Atsma, F. ; Hoogeboom, T.J. ; Blijlevens, N.M.A. ; Nijhuis-van der Sanden, M.W.G.2018, Article / Letter to editor (Physiotherapy Theory and Practice, vol. 16, (2018), pp. 1-10) -
Physical exercise prior to hematopoietic stem cell transplantation: A feasibility study. Haren, I.E.P.M. van ; Staal, J.B. ; Potting, C.M. ; Atsma, F. ; Hoogeboom, T.J. ; Blijlevens, N.M.A. ; -van der Sanden, M.W.G. Nijhuis2018, Article / Letter to editor (Physiotherapy Theory and Practice, vol. 34, iss. 10, (2018), pp. 747-756)PURPOSE: This study explores the feasibility and preliminary effectiveness of an exercise program in people scheduled for hematopoietic stem cell transplantation (HSCT). METHODS: In this controlled clinical trial, we compare pre-transplantation exercise to no exercise in the waiting period for an allogeneic of autologous HSCT. The supervised individually tailored exercise program (4-6 weeks) consisted of aerobic endurance, muscle strength, and relaxation exercises, administered twice a week in the period prior to HSCT. Feasibility was determined based on inclusion rate, attrition rate, adherence to intervention, safety, and satisfaction (0-10). Preliminary effectiveness was determined primarily by self-perceived physical functioning, quality of life (QOL), and fatigue. Secondary outcomes were global perceived effect (GPE), blood counts, hospital stay, and physical fitness. RESULTS: Forty-six patients were eligible, of whom 29 (69%) participated: 14 in the intervention group and 15 in the control group. The adherence rate to training was 69%. No adverse events or injuries occurred. Satisfaction of training conditions was high (mean 9.2 ±1.3). Positive (follow-up) trends in favor of the intervention group were found for self-perceived physical functioning, QOL, fatigue, GPE, blood counts, and hospital stay. CONCLUSION: Exercise prior to HSCT is safe and feasible, and positive trends suggest favorable preliminary effectiveness. Adherence to the exercise program needs to be optimized in a future trial.
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