Browsing Han Publications without organization data by Author "Hoedemaekers, A."

Now showing items 1-2 of 2

Biomarkers in delirious patients at the critical care unit
Boogaard, Mark van den ; Hoeven, Hans van der ; Quinn, K. ; Schoonhoven, Lisette ; Pickkers, Peter ; Hoedemaekers, A.
2010, Article / Letter to editor (Intensive Care Medicine, vol. 2010, iss. 36, (2010), pp. suppl.-2 s221)Delirium occurs frequently in critically ill patients, and especially in severely ill and in infectious patients. Although several causal pathways for delirium have been described, the role of biomarkers in ICU patients is unknown. We investigated potential differences in various serum biomarkers between delirious and non-delirious ICU patients with and without an infection.
Endotoxemia-induced inflammation and the effect on the human brain
Schoonhoven, Lisette ; Boogaard, Mark van den ; Hoeven, Hans van der ; Fick, I. ; Ramakers, B. ; Alfen, N. van ; Werf, S. van der ; Verbeek, M. ; Hoedemaekers, A. ; Pickkers, Peter
2010, Article / Letter to editor (Critical Care, vol. 2010, iss. 14, (2010), pp. R81)Effects of systemic inflammation on cerebral function are not clear, as both inflammation-induced encephalopathy as well as stress-hormone mediated alertness have been described. Experimental endotoxemia (2 ng/kg Escherichia coli lipopolysaccharide [LPS]) was induced in 15 subjects, whereas 10 served as controls. Cytokines (TNF-a, IL-6, IL1-RA and IL-10), cortisol, brain specific proteins (BSP), electroencephalography (EEG) and cognitive function tests (CFTs) were determined. Short-term systemic inflammation does not provoke or explain the occurrence of septic encephalopathy, but primarily results in an inflammation-mediated increase in cortisol and alertness.

Now showing items 1-2 of 2

Browsing Han Publications without organization data by Author "Hoedemaekers, A."

Browse

All of HAN Publications

This Collection